Thanks for all the comments and advice.
So far all I have is the plain baseboard, it is ring of eight 600mm x 1200mm boards.
I am thinking I will put a back-scene support around 3 sides and the main scenic area would have most of the track at base-board level with an elevated "branchline" at the rear of the scene which would run in a loop and have an access ramp at the very back. I plan to have scenic breaks at the left and right of the front portion, at least one of those would be a rail over-bridge I am thinking, and I have to use that retaining wall kit somewhere
I am not big into shunting hence the desire for multiple roundy-roundy levels to allow me run multiple trains simultaneously. I would like to have landscape on the sides and some at the back maybe. I would prefer to keep point work on the upper level to a minimum so that I dont have to worry about failing point motors in inaccessible places. The more complex track work would be on the lower level with point motors easily accessible from under the baseboards. The clearances are really only critical where there lower level main-line crosses under the upper level line at either end of the front scenic section.
I have been following Charlie Bishop's Helix build on Chadwick and he had to reduce the gradient on the helix alright and used the 'powerbase', hopefully i can get away with more as my trains are shorter than his.
@Broithe mentions 4in/8ft (~4%) without too many problems, that sounds encouraging and I have the space for that. Once I get the backscene boards on I can do some trials when there is less chance of a loco taking a dive over the edge.